What is an ischemic stroke?

An ischemic stroke is a medical emergency that happens when a blood vessel becomes blocked in your brain, interrupting blood flow to a portion of the brain. Brain cells can’t function when they are deprived of the vital oxygen and nutrients that your blood cells carry. Ischemic strokes are the most common type of stroke, accounting for nearly 90% of all strokes. The other type of stroke is hemorrhagic stroke, when there is bleeding in the brain.

If you think you or someone else is having a stroke, call 911 right away. Quick diagnosis and treatment can save a life—every second matters.

Types of ischemic strokes

There are two main types of ischemic strokes:

  • Thrombotic stroke: This happens when a blood clot forms in the brain and blocks blood flow.
  • Embolic stroke: This occurs when a clot forms elsewhere in the body, travels to the brain, and gets stuck in a blood vessel.

What is a transient ischemic attack (TIA)?

A transient ischemic attack (TIA) , also known as a "mini-stroke," causes stroke-like symptoms but doesn’t cause lasting damage. However, it’s a serious warning sign that a major stroke could happen soon. If you or someone you know experiences a TIA, seek emergency medical care right away.

Ischemic stroke symptoms

Ischemic stroke symptoms typically come on quickly without another apparent cause. Symptoms can differ depending on the part of the brain being deprived of blood. Men and women both experience many of the same stroke symptoms, but some symptoms, such as disorientation, fatigue, nausea, vomiting and weakness, may be more common in women.

Symptoms of an ischemic stroke include:

  • Confusion
  • Changes to mood or personality
  • Difficulty with speaking and understanding, such as slurring of speech
  • Difficulty walking
  • Dizziness
  • Drooping of the face, especially on one side
  • Drowsiness
  • Fatigue
  • Loss of balance
  • Nausea or vomiting
  • Weakness in your arm or leg, often on just one side of your body
  • Problems with seeing, hearing, touch and other senses
  • Trouble with coordination
  • Unconsciousness or coma
  • Numbness or tingling, especially on one side of the body

    When to see a doctor

    See your doctor anytime you experience stroke symptoms that come on swiftly. Call 911 immediately if you or someone else experiences the “B.E. F.A.S.T.” stroke symptoms:

    • Balance: The person loses balance or becomes uncoordinated.
    • Eyes: The person has vision problems in one or both eyes.
    • Face: Their face droops, or they have uneven facial expressions.
    • Arms: Their arm is weak or drifts down when held up.
    • Speech: Their speech is slurred or hard to understand.
    • Time: It is time to call 911.

    Ischemic stroke causes

    The most common cause of ischemic stroke is a condition called atherosclerosis, where fatty deposits (called plaque) build up inside blood vessels. These deposits can cause two types of blockages:

    • Cerebral thrombosis happens when a blood clot forms where plaque has built up in a vessel that supplies blood to the brain. This can occur in the small vessels in the brain.
    • Cerebral embolism occurs when a blood clot forms in the large arteries in the chest or neck. The clot can break loose, travel through the bloodstream, and get stuck in smaller brain vessels. Sometimes blood clots can block an artery in the neck completely, causing the stroke.

    The second most common cause of ischemic stroke is embolism, or blockage in a blood vessel, from the heart that travels to the brain. An irregular heartbeat called atrial fibrillation  is the most likely cause of this type of stroke. There are other possible causes of embolic stroke, such as:

    • Heart failure
    • Clotting disorders
    • Infections in the bloodstream
    • A hole in the heart, a condition called a patent foramen ovale

    Ischemic stroke risk factors

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    While you never know exactly when a stroke will happen, ischemic stroke has known risk factors. In some cases, you can control your risk through lifestyle changes or by working with your doctor. Sometimes, you can’t control your risk factors, but knowing what they are helps you take extra steps to protect yourself.

    Risk factors you cannot control

    • Age: People of any age can have a stroke, but your risk increases as you get older.
    • Family history: Your risk is higher if someone in your close family—a parent, brother or sister—has had a stroke.
    • History of heart attack: Heart attacks share many stroke risk factors, such as high cholesterol.
    • History of stroke or TIA: One stroke or TIA increases the likelihood of having another stroke.
    • Race: Black and Hispanic people have a higher risk than white people.
    • Sex: Women’s risk of stroke is higher than men’s.

    Lifestyle risk factors

    • Drinking too much: Consuming excess alcohol can increase blood pressure, a stroke risk factor.
    • Eating habits: A diet high in sodium, unhealthy fats and sugar can lead to excess weight, diabetes, high blood pressure and high cholesterol, which are all stroke risk factors.
    • Sedentary lifestyle: Not moving enough can contribute to health problems that raise stroke risk.
    • Smoking: Chemicals in cigarettes can damage blood vessels. Smoking also raises blood pressure.

    Medical risk factors

    • Atrial fibrillation: This heart rhythm disorder can cause blood clots, which can come loose and block blood vessels in the brain.
    • Carotid artery disease: Plaque buildup in the carotid arteries in your neck, which bring blood to your brain, can contribute to blockages.
    • Excess weight: Being obese increases your risk of diabetes, high blood pressure and heart disease, each of which can increase stroke risk.
    • Diabetes: High blood sugar can cause fatty deposits and blood clots that can lead to a stroke.
    • High blood pressure: High blood pressure damages blood vessels, making them more prone to narrowing and blockages.
    • High cholesterol: High cholesterol can also damage blood vessels, and it contributes to plaque in the arteries.
    • Obstructive sleep apnea (OSA): OSA causes you to stop breathing when you sleep, which can increase your risk of heart disease and stroke.
    • Sickle cell disease: Red blood cells have a curved shape and are more likely to stick together. Sickle cells can become stuck in a blood vessel, blocking blood flow to the brain.

    Complications

    Ischemic stroke can have severe complications and may even be fatal. The type and severity of complications depend on the location of the blockage and how much of the brain was damaged. Ischemic stroke complications include:

    • Venous blood clots: If you are unable to walk around after a stroke, blood clots may form.
    • Incontinence: You may have trouble controlling your bladder or bowels.
    • Language problems: These include difficulty communicating or understanding.
    • Loss of physical senses: You may have difficulty with hearing, sight or sensation.
    • Physical weakness or difficulty moving: This can hinder your ability to work or perform daily tasks.
    • Problems with thinking and memory: You may have issues with concentration or decision-making.
    • Seizures: These are more likely in the first few weeks after a stroke but can happen at any time.
    • Speech and swallowing problems: These can affect eating and talking. You can get pneumonia if you inhale food or drink into your lungs.

    How is an ischemic stroke diagnosed?

    An ischemic stroke is a serious medical emergency, and getting help fast can save a life. If you or someone around you shows signs of a stroke, call 911 immediately.

    Doctors diagnose strokes in the emergency room by asking about your medical history, checking your brain and nerve function with a physical exam and doing imaging tests. Since quick treatment is key to preventing serious damage, doctors work fast to confirm a stroke and start care right away. Your ER doctor might order a computerized tomography (CT) scan of your brain to check for a stroke. However, if it's an ischemic stroke caused by a blocked blood vessel, it might not show up right away because early changes in the brain can be too subtle for the scan to detect. Still, the scan helps doctors quickly decide on the best emergency treatment.

    • Medical history and exam

      If you're confused or having trouble speaking, doctors may ask a family member for details about your medical history. You or your loved one should share any history of high blood pressure, high cholesterol, diabetes or previous strokes. It’s also important to mention lifestyle factors like smoking or alcohol use.

      It is helpful to share the timing of the onset of your symptoms to assist the treatment team in determining your eligibility for certain stroke treatments. The team will also request a list of your current medications. It is important to share if you are taking blood-thinning medications.

      In the emergency room, a specialized stroke team will quickly assess your speech, facial movements, arm and leg strength, sensation, coordination and balance to determine if you're having a stroke.

    • Blood tests

      There isn’t a single blood test that can confirm an ischemic stroke, but doctors use blood tests to rule out other conditions and find possible causes of your symptoms.

      • Complete blood count (CBC): Checks overall blood health, including infection, anemia and clotting ability.
      • Coagulation tests: Measure how fast your blood clots, which can help determine if a stroke was caused by a clotting issue.
      • Electrolyte tests: Detect imbalances that might cause weakness, confusion or other stroke-like symptoms.
      • Blood sugar test: Checks for high or low blood sugar, which can sometimes mimic a stroke.
      • C-reactive protein (CRP) test: Looks for inflammation that may indicate artery damage.
      • Liver and kidney function tests: Help identify other health conditions that could contribute to stroke risk.
    • Imaging tests

      Your provider will order tests to view blood flow within your brain and see whether you are having a stroke, as well as its type and location. This helps them determine the correct course of treatment.

      • Computerized tomography (CT) scan: A CT scan provides immediate information about the type, location and size of a stroke.
      • CT angiogram: An angiogram, or angiography, shows blood flow in your brain and reveals any bleeds or blockages.
      • Magnetic resonance imaging (MRI) scan: MRI uses magnets and radio waves to create a detailed image of the arteries, veins and soft tissues in your brain. This image can characterize the size and location of a stroke, even if the stroke is very small.
      • Electrocardiogram (EKG or ECG): This test records the heart's electrical activity and helps detect irregular heart rhythms, such as atrial fibrillation, which can increase the risk of blood clots leading to an ischemic stroke.
      • Electroencephalogram (EEG): This test measures brain wave activity and helps rule out seizures or other neurological conditions that may cause stroke-like symptoms. However, it is not typically used as a primary test to diagnose ischemic stroke.

    Ischemic stroke treatment

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    If someone has stroke symptoms, getting emergency medical care right away is critical. Fast treatment can save lives, limit brain damage and improve recovery. Stroke treatment focuses on preventing serious complications, reducing the risk of another stroke and minimizing long-term effects. Rehabilitation is also an important part of recovery, helping individuals regain strength, independence and quality of life.

    Medication

    Doctors may use a medication called tissue plasminogen activator (tPA or alteplase) or Tenecteplase (TNK) to break up blood clots and restore blood flow to the brain. For the best results, the clot-busting medication should be given within 4.5 hours of when stroke symptoms first appear. That’s why it’s so important to get emergency care right away.

    If the clot-buster medication isn’t an option, doctors may prescribe aspirin or other blood thinners to help prevent new clots from forming. These medications can also help lower the risk of future strokes.

    After a stroke, some people may need medications to reduce brain swelling or pressure. Others might require oxygen therapy or IV fluids to stay hydrated and get the nutrients they need for recovery.

    Surgery

    Surgery to remove a blockage from a brain artery is called thrombectomy. This surgery may be done up to 24 hours after stroke symptoms begin.

    Generally, doctors use thrombectomy when a blockage occurs in a blood vessel large enough to insert a catheter and special surgical tools.

    In thrombectomy, a doctor threads a catheter through an artery in your groin to reach the blocked artery. Your team will inject dye into the catheter so your surgeon can use imaging to view the artery and perform the procedure. The doctor then inserts a tool that grabs and removes the clot. To help prevent future strokes, doctors may recommend:

    • Carotid endarterectomy: A surgical procedure to remove built-up fatty plaque from the inside of the carotid artery, improving blood flow to the brain.
    • Carotid artery stenting: A minimally invasive procedure where a small mesh tube (stent) is placed inside the carotid artery using a catheter. The stent helps keep the artery open and reduces the risk of blockages.

    Stroke rehabilitation

    After a stroke, you will receive rehabilitation to help you recover skills and abilities. Rehabilitation for stroke focuses on any aspect of your life affected by the stroke, including thinking, speaking, movement and everyday activities.

    • Cognitive therapy: This helps you with focus and memory.
    • Occupational therapy: You learn strategies to perform activities of daily living, such as dressing, brushing your teeth and cooking.
    • Speech-language therapy: Speech-language therapists help with forming and understanding words and with issues related to swallowing.
    • Physical therapy: You build skills and abilities to help with balance, coordination and strength.
    Are you concerned about strokes? Learn whether you’re at risk.

    Find a location near you

    If you or a loved one exhibits signs of an ischemic stroke, seek medical attention immediately. Our hospitals across North and Central Texas have specialized stroke care teams prepared to evaluate and treat potential stroke cases quickly. Find a nearby location to receive prompt care and lower the chances of severe complications or a full stroke.

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    Frequently asked questions

    • What is the most common cause of ischemic stroke?

      The most common cause of an ischemic stroke is a blood clot blocking a blood vessel in the brain. This often happens because of a buildup of fatty deposits, known as plaque, in the arteries—a condition called atherosclerosis. As the arteries narrow and harden, it's easier for clots to form, which can lead to a stroke.

    • What percentage of strokes are ischemic?

      About 87% of all strokes are ischemic, meaning they happen when a blood clot or blockage slows or stops blood flow to the brain. Since the brain needs a steady supply of oxygen and nutrients to work properly, any interruption can be serious and requires quick medical attention.

    • Can a mild head injury cause ischemic stroke?

      Yes, even a mild head injury can raise the risk of an ischemic stroke. Damage to blood vessels can lead to blockages, increasing stroke risk—especially in the first four months but lasting up to five years. Multiple head injuries further increase the risk, no matter your age or background.

    • Are ischemic strokes dangerous?

      Yes, an ischemic stroke is a serious medical emergency. It happens when a blood clot or fatty buildup blocks blood flow to the brain. Without oxygen and nutrients, brain cells can become damaged, which can lead to long-term problems or even be life-threatening. Quick treatment is crucial to reduce the risk of lasting effects.

    • Are ischemic strokes hereditary?

      Yes, ischemic strokes can run in families, but lifestyle and health choices also play a significant role. Certain genes can increase stroke risk and affect recovery. If you have a family history of stroke, managing blood pressure, cholesterol and other risk factors can help lower your chances.

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